Human GUCA1A protein (Recombinant) (N-His) (STJP015754)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human GUCA1A-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | GUCA1A |
| Gene ID | 118142757/2978 |
| Uniprot ID | GUC1A_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Gly201 |
Additional Info
| Function | Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure. May be involved in cone photoreceptor light response and recovery of response in bright light. |
| Protein Name | Guanylyl Cyclase-Activating Protein 1Gcap 1Guanylate Cyclase Activator 1a |
| Database Links | Reactome: R-HSA-2514859 |
| Cellular Localisation | MembraneLipid-AnchorPhotoreceptor Inner SegmentCell ProjectionCiliumPhotoreceptor Outer SegmentPresent At Higher Levels In Cone Than In Rod Outer SegmentsSubcellular Location Is Not Affected By Light Or Dark Conditions |
| Alternative Protein Names | Guanylyl Cyclase-Activating Protein 1 proteinGcap 1 proteinGuanylate Cyclase Activator 1a proteinGUCA1A proteinC6orf131 proteinGCAP proteinGCAP1 proteinGUCA1 protein |
Information sourced from Uniprot.org