Human GUCA1A protein (Recombinant) (N-His) (STJP015754)

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STJP015754
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Short Description :Recombinant-Human GUCA1A-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:GUCA1A
Gene ID:118142757/2978
Uniprot ID:GUC1A_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Gly201
Function Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure. May be involved in cone photoreceptor light response and recovery of response in bright light.
Protein Name Guanylyl Cyclase-Activating Protein 1
Gcap 1
Guanylate Cyclase Activator 1a
Database Links Reactome: R-HSA-2514859
Cellular Localisation Membrane
Lipid-Anchor
Photoreceptor Inner Segment
Cell Projection
Cilium
Photoreceptor Outer Segment
Present At Higher Levels In Cone Than In Rod Outer Segments
Subcellular Location Is Not Affected By Light Or Dark Conditions
Alternative Protein Names Guanylyl Cyclase-Activating Protein 1 protein
Gcap 1 protein
Guanylate Cyclase Activator 1a protein
GUCA1A protein
C6orf131 protein
GCAP protein
GCAP1 protein
GUCA1 protein

Information sourced from Uniprot.org

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