Human GRIA3 (Glutamate Receptor, Ionotropic, AMPA 3) Sandwich ELISA Kit (STJE0009295)
SPECIFICATIONS
General Information
| Short Description | This GRIA3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.116ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | GRIA3 |
| Gene ID | 2892 |
| Uniprot ID | GRIA3_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic acid, and kainic acid. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system and plays an important role in fast excitatory synaptic transmission by inducing long-term potentiation. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse upon entry of calcium. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
| Protein Name | Glutamate Receptor 3Glur-3Ampa-Selective Glutamate Receptor 3Glur-CGlur-K3Glutamate Receptor Ionotropic - Ampa 3 |
| Database Links | Reactome: R-HSA-399710Reactome: R-HSA-399719Reactome: R-HSA-416993Reactome: R-HSA-438066Reactome: R-HSA-8849932 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell MembranePostsynaptic Density Membrane |
| Alternative ELISA Names | Glutamate Receptor 3 ELISA kitGlur-3 ELISA kitAmpa-Selective Glutamate Receptor 3 ELISA kitGlur-C ELISA kitGlur-K3 ELISA kitGlutamate Receptor Ionotropic - Ampa 3 ELISA kitGRIA3 ELISA kitGluA3 ELISA kitGLUR3 ELISA kitGLURC ELISA kit |
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Information sourced from Uniprot.org