Human GPNMB protein (Recombinant-Active) (C-His) (STJP012111)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human GPNMB-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Immobilised human GPNMB at 1 Mu g/mL (100 Mu L/well) can bind anti-GPNMB Rabbit pAb with a linear range of 0.976-116.5 ng/mL. |
Target Information
| Gene Symbol | GPNMB |
| Gene ID | 10457 |
| Uniprot ID | GPNMB_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys23-Pro486 |
Additional Info
| Function | Could be a melanogenic enzyme. |
| Protein Name | Transmembrane Glycoprotein NmbHematopoietic Growth Factor Inducible Neurokinin-1 Type |
| Database Links | Reactome: R-HSA-8857538 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinMelanosome MembraneEarly Endosome MembraneIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Protein Names | Transmembrane Glycoprotein Nmb proteinHematopoietic Growth Factor Inducible Neurokinin-1 Type proteinGPNMB proteinHGFIN proteinNMB proteinUNQ1725 proteinPRO9925 protein |
Information sourced from Uniprot.org