Human GPNMB protein (Recombinant-Active) (C-His) (STJP012111)

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STJP012111-100
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Short Description :Recombinant-Active-Human GPNMB-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:<0.1 EU/Mu g of the protein by the LAL method.
Immunoreactivity:Immobilised human GPNMB at 1 Mu g/mL (100 Mu L/well) can bind anti-GPNMB Rabbit pAb with a linear range of 0.976-116.5 ng/mL.
Gene Symbol:GPNMB
Gene ID:10457
Uniprot ID:GPNMB_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Lys23-Pro486
Function Could be a melanogenic enzyme.
Protein Name Transmembrane Glycoprotein Nmb
Hematopoietic Growth Factor Inducible Neurokinin-1 Type
Database Links Reactome: R-HSA-8857538
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Melanosome Membrane
Early Endosome Membrane
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Protein Names Transmembrane Glycoprotein Nmb protein
Hematopoietic Growth Factor Inducible Neurokinin-1 Type protein
GPNMB protein
HGFIN protein
NMB protein
UNQ1725 protein
PRO9925 protein

Information sourced from Uniprot.org