Human GM-CSF protein (Recombinant) (STJP000349)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenDNA sequence encoding the extracellular domain of Human CSF2 including a N-terminal His tag was expressed in HEK293 Cells. NA
General Information
| Short Description | Recombinant-Human GM-CSF-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
| Storage Instruction | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity | The activity was determined by its ability to bind in functional ELISA assay. NA |
Target Information
| Gene Symbol | CSF2 |
| Gene ID | 1437 |
| Uniprot ID | CSF2_HUMAN |
| Immunogen | DNA sequence encoding the extracellular domain of Human CSF2 including a N-terminal His tag was expressed in HEK293 Cells. NA |
| Immunogen Region | ECD |
| Immunogen Sequence | APARSPSPST QPWEHVNAIQ EARRLLNLSR DTAAEMNETV EVISEMFDLQ EPTCLQTRLE LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFESFKENL KDFLLVIPFD NA |
Additional Info
| Function | Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. |
| Protein Name | Granulocyte-Macrophage Colony-Stimulating FactorGm-CsfColony-Stimulating FactorCsfMolgramostinSargramostim |
| Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-6783783Reactome: R-HSA-8939246Reactome: R-HSA-912526 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Granulocyte-Macrophage Colony-Stimulating Factor proteinGm-Csf proteinColony-Stimulating Factor proteinCsf proteinMolgramostin proteinSargramostim proteinCSF2 proteinGMCSF protein |
Information sourced from Uniprot.org