Human GLYATL2 protein (Recombinant) (His-Tag) (STJP018650)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GLYATL2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 50% Glycerol, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GLYATL2 |
| Gene ID | 219970 |
| Uniprot ID | GLYL2_HUMAN |
| Accession Number | NP_659453 |
| Immunogen | Human |
| Immunogen Region | 1-294aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMLVLHNS QKLQILYKSL EKSIPESIKV YGAIFNIKDK NPFNMEVLVD AWPDYQIVIT RPQKQEMKDD QDHYTNTYHI FTKAPDKLEE VLSYSNVISW EQTLQIQGCQ EGLDEAIRKV ATSKSVQVDY MKTILFIPEL PKKHKTSSND KMELFEVDDD NKEGNFSNMF LDASHAGLVN EHWAFGKNER SLKYIERCLQ DFLGFGVL |
Additional Info
| Tissue Specificity | Expressed at highest levels in salivary gland and trachea. Also detected in thyroid gland, spinal cord, prostate, lung and fetal brain. |
| Post Translational Modifications | Acetylation at Lys-19 drastically decreases the production of N-oleoyl and N-arachidonoyl glycines. |
| Function | Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0-CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine. |
| Protein Name | Glycine N-Acyltransferase-Like Protein 2Acyl-Coa -Glycine N-Acyltransferase-Like Protein 2 |
| Database Links | Reactome: R-HSA-177128Reactome: R-HSA-177135Reactome: R-HSA-9749641 |
| Cellular Localisation | Endoplasmic Reticulum |
| Alternative Protein Names | Glycine N-Acyltransferase-Like Protein 2 proteinAcyl-Coa -Glycine N-Acyltransferase-Like Protein 2 proteinGLYATL2 protein |
Information sourced from Uniprot.org