| Function | Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69. |
| Protein Name | Galectin-1Gal-114 Kda Laminin-Binding ProteinHlbp1414 Kda LectinBeta-Galactoside-Binding Lectin L-14-IGalaptinHblHplLactose-Binding Lectin 1Lectin Galactoside-Binding Soluble 1Putative Mapk-Activating Protein Pm12S-Lac Lectin 1 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixCytoplasmCan Be SecretedThe Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion |
| Alternative Antibody Pair Names | Galectin-1 antibody pairGal-1 antibody pair14 Kda Laminin-Binding Protein antibody pairHlbp14 antibody pair14 Kda Lectin antibody pairBeta-Galactoside-Binding Lectin L-14-I antibody pairGalaptin antibody pairHbl antibody pairHpl antibody pairLactose-Binding Lectin 1 antibody pairLectin Galactoside-Binding Soluble 1 antibody pairPutative Mapk-Activating Protein Pm12 antibody pairS-Lac Lectin 1 antibody pairLGALS1 antibody pair |
Information sourced from Uniprot.org
