Human GAL1 (Galectin-1) Antibody Pair (STJAP00463)

SPECIFICATIONS
HostGoat/Rabbit
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Human GAL1 protien.
Detection Immunogen: Recombinant Human GAL1 protien.
STJAP00463-50
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General Information

Short DescriptionThis GAL1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
ApplicationsELISA
HostGoat/Rabbit
ReactivityHuman
NoteFOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Product Properties

ConjugationUnconjugated/Biotin
Concentration0.5 mg/mL
PurificationCapture Purification: Antigen Affinity.
Detection Purification: Protein A or G.
FormulationCapture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.
Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5.
Storage InstructionStore at-20°C for the long term, and avoid freeze-thaw cycles.
Determination MethodColormetric

Target Information

Gene SymbolLGALS1
Gene ID3956
Uniprot IDLEG1_HUMAN
ImmunogenCapture immunogen: Recombinant Human GAL1 protien.
Detection Immunogen: Recombinant Human GAL1 protien.
Sample TypeSerum, plasma and other biological fluids

Additional Info

Function Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69.
Protein Name Galectin-1
Gal-1
14 Kda Laminin-Binding Protein
Hlbp14
14 Kda Lectin
Beta-Galactoside-Binding Lectin L-14-I
Galaptin
Hbl
Hpl
Lactose-Binding Lectin 1
Lectin Galactoside-Binding Soluble 1
Putative Mapk-Activating Protein Pm12
S-Lac Lectin 1
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Cytoplasm
Can Be Secreted
The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10
It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Antibody Pair Names Galectin-1 antibody pair
Gal-1 antibody pair
14 Kda Laminin-Binding Protein antibody pair
Hlbp14 antibody pair
14 Kda Lectin antibody pair
Beta-Galactoside-Binding Lectin L-14-I antibody pair
Galaptin antibody pair
Hbl antibody pair
Hpl antibody pair
Lactose-Binding Lectin 1 antibody pair
Lectin Galactoside-Binding Soluble 1 antibody pair
Putative Mapk-Activating Protein Pm12 antibody pair
S-Lac Lectin 1 antibody pair
LGALS1 antibody pair

Information sourced from Uniprot.org

Citations

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Common questions about Human GAL1 (Galectin-1) Antibody Pair (STJAP00463)

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