Human FOLR2 protein (Recombinant) (N-His) (STJP004093)

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STJP004093
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Short Description :Recombinant-Human FOLR2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:FOLR2
Gene ID:2350
Uniprot ID:FOLR2_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Thr17-Asn230
Post Translational Modifications N-glycosylated.
Function Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Protein Name Folate Receptor Beta
Fr-Beta
Folate Receptor 2
Folate Receptor - Fetal/Placental
Placental Folate-Binding Protein
Fbp
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-196757
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative Protein Names Folate Receptor Beta protein
Fr-Beta protein
Folate Receptor 2 protein
Folate Receptor - Fetal/Placental protein
Placental Folate-Binding Protein protein
Fbp protein
FOLR2 protein

Information sourced from Uniprot.org

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