Human FOLR2 protein (Recombinant) (N-His) (STJP004093)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FOLR2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FOLR2 |
| Gene ID | 2350 |
| Uniprot ID | FOLR2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr17-Asn230 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. |
| Protein Name | Folate Receptor BetaFr-BetaFolate Receptor 2Folate Receptor - Fetal/PlacentalPlacental Folate-Binding ProteinFbp |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196757 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecreted |
| Alternative Protein Names | Folate Receptor Beta proteinFr-Beta proteinFolate Receptor 2 proteinFolate Receptor - Fetal/Placental proteinPlacental Folate-Binding Protein proteinFbp proteinFOLR2 protein |
Information sourced from Uniprot.org