Post Translational Modifications | The extracellular domain is cleaved and released from the cell membrane. N-Glycosylated. |
Function | Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. |
Protein Name | Fibronectin Type Iii Domain-Containing Protein 5Fibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPeroxisome MembraneImported In Peroxisomes Through The Pex5 Receptor PathwayIrisin: SecretedDetected In The Blood Of Individuals Subjected To Endurance Exercise |
Alternative Protein Names | Fibronectin Type Iii Domain-Containing Protein 5 proteinFibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin proteinFNDC5 proteinFRCP2 protein |
Information sourced from Uniprot.org