Human FNDC5 protein (Recombinant) (N-His) (STJP005708)

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STJP005708
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human FNDC5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FNDC5
Gene ID: 252995
Uniprot ID: FNDC5_HUMAN
Immunogen Region: Met76-Lys211
Immunogen: Homo sapiens (Human)
Post Translational Modifications The extracellular domain is cleaved and released from the cell membrane. N-Glycosylated.
Function Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
Protein Name Fibronectin Type Iii Domain-Containing Protein 5
Fibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Peroxisome Membrane
Imported In Peroxisomes Through The Pex5 Receptor Pathway
Irisin: Secreted
Detected In The Blood Of Individuals Subjected To Endurance Exercise
Alternative Protein Names Fibronectin Type Iii Domain-Containing Protein 5 protein
Fibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin protein
FNDC5 protein
FRCP2 protein

Information sourced from Uniprot.org

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