Human FMO3 protein (Recombinant) (N-His) (STJP004547)

Name: Human FMO3 protein (Recombinant) (N-His) (STJP004547)
SKU: STJP004547
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP004547

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Short Description	Recombinant-Human FMO3-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.
Protein Name	Flavin-Containing Monooxygenase 3 Dimethylaniline Monooxygenase N-Oxide-Forming 3 Dimethylaniline Oxidase 3 Fmo Ii Fmo Form 2 Hepatic Flavin-Containing Monooxygenase 3 Fmo 3 Trimethylamine Monooxygenase
Database Links	Reactome: R-HSA-217271 Reactome: R-HSA-5579019
Cellular Localisation	Microsome Membrane Single-Pass Membrane Protein Endoplasmic Reticulum Membrane
Alternative Protein Names	Flavin-Containing Monooxygenase 3 protein Dimethylaniline Monooxygenase N-Oxide-Forming 3 protein Dimethylaniline Oxidase 3 protein Fmo Ii protein Fmo Form 2 protein Hepatic Flavin-Containing Monooxygenase 3 protein Fmo 3 protein Trimethylamine Monooxygenase protein FMO3 protein

Information sourced from Uniprot.org