Human FFAR1 (Free Fatty Acid Receptor 1) Sandwich ELISA Kit (STJE0008844)
SPECIFICATIONS
General Information
| Short Description | This FFAR1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.54ng/mL |
| Detection Limit | 1.56-100ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | FFAR1 |
| Gene ID | 2864 |
| Uniprot ID | FFAR1_HUMAN |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in brain and pancreas. Detected in pancreatic beta cells. |
| Post Translational Modifications | |
| Function | G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis.receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. Mediates the anti-inflammatory effects of omega-3 polyunsaturated fatty acids (PUFAs) via inhibition of NLRP3 inflammasome activation. |
| Protein Name | Free Fatty Acid Receptor 1G-Protein Coupled Receptor 40 |
| Database Links | Reactome: R-HSA-381771Reactome: R-HSA-400511Reactome: R-HSA-416476Reactome: R-HSA-434316Reactome: R-HSA-444209 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Free Fatty Acid Receptor 1 ELISA kitG-Protein Coupled Receptor 40 ELISA kitFFAR1 ELISA kitGPR40 ELISA kit |
| output |
Information sourced from Uniprot.org