Name: Human FBLIM1 protein (Recombinant) (His-Tag) (STJP018220)
SKU: STJP018220
Availability: InStock

Human FBLIM1 protein (Recombinant) (His-Tag) (STJP018220)

SKU:

STJP018220

£134.50 - £738.50

Short Description :	Recombinant-Human FBLIM1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	0.25 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FBLIM1
Gene ID:	54751
Uniprot ID:	FBLI1_HUMAN
Accession Number:	NP_060026
Immunogen:	Human
Immunogen Region:	1-373aa
Immunogen Sequence:	MGSSHHHHHH SSGLVPRGSH MGSMASKPEK RVASSVFITL APPRRDVAVA EEVRQAVCEA RRGRPWEAPA PMKTPEAGLA GRPSPWTTPG RAAATVPAAP MQLFNGGCPP PPPVLDGEDV LPDLDLLPPP PPPPPVLLPS EEEAPAPMGA SLIADLEQLH LSPPPPPPQA PAEGPSVQPG PLRPMEEELP PPPAEPVEKG ASTDICAFCH KTVSPRELAV EAMKRQYH

Tissue Specificity	Isoform 1 and isoform 3 are expressed in heart, kidney, lung, pancreas, placenta and platelets. Isoform 2 is expressed in brain, heart, kidney, lung, pancreas, placenta, skeletal muscle and platelets.
Function	Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Protein Name	Filamin-Binding Lim Protein 1 Fblp-1 Migfilin Mitogen-Inducible 2-Interacting Protein Mig2-Interacting Protein
Database Links	Reactome: R-HSA-446353
Cellular Localisation	Cell Junction Focal Adhesion Cytoplasm Cytoskeleton Stress Fiber Associated With Actin Stress Fiber At Cell-Ecm Focal Adhesion Sites Isoform 1 And Isoform 3 Are Recruited And Localized At Actin Stress Fibers And Clustered At Cell-Emc Adhesion Sites Through Interaction With Fermt2 Isoform 2 Is Localized At Actin Stress Fibers
Alternative Protein Names	Filamin-Binding Lim Protein 1 protein Fblp-1 protein Migfilin protein Mitogen-Inducible 2-Interacting Protein protein Mig2-Interacting Protein protein FBLIM1 protein FBLP1 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP016871	Human ACOT13 protein (Recombinant) (His-Tag) (STJP016871)	E.coli	SDS-PAGE
STJP019004	Human Opticin protein (Recombinant) (His-Tag) (STJP019004)	E.coli	SDS-PAGE/Denatured
STJP019002	Human BNIP1 protein (Recombinant) (His-Tag) (STJP019002)	E.coli	SDS-PAGE/Denatured
STJP019010	Human CREB3L2 protein (Recombinant) (His-Tag) (STJP019010)	E.coli	SDS-PAGE
STJP019006	Human Napsin A protein (Recombinant) (His-Tag) (STJP019006)	E.coli	SDS-PAGE/Denatured

Human FBLIM1 protein (Recombinant) (His-Tag) (STJP018220)

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