Human ETS2 protein (Recombinant) (His-Tag) (STJP018836)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ETS2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M urea |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ETS2 |
| Gene ID | 2114 |
| Uniprot ID | ETS2_HUMAN |
| Accession Number | NP_005230.1 |
| Immunogen | Human |
| Immunogen Region | 1-469aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Phosphorylation by CDK10 at Ser-220 and Ser-225 creates a phosphodegron that targets ETS2 for proteasomal degradation. |
| Function | Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription. |
| Protein Name | Protein C-Ets-2 |
| Database Links | Reactome: R-HSA-2559585 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Protein C-Ets-2 proteinETS2 protein |
Information sourced from Uniprot.org