Human ERP44 protein (Recombinant) (His-Tag) (STJP016818)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ERP44-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ERP44 |
| Gene ID | 23071 |
| Uniprot ID | ERP44_HUMAN |
| Accession Number | NP_055866 |
| Immunogen | Human |
| Immunogen Region | 30-406aa |
| Immunogen Sequence |
Additional Info
| Function | Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum. |
| Protein Name | Endoplasmic Reticulum Resident Protein 44Er Protein 44Erp44Thioredoxin Domain-Containing Protein 4 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Protein Names | Endoplasmic Reticulum Resident Protein 44 proteinEr Protein 44 proteinErp44 proteinThioredoxin Domain-Containing Protein 4 proteinERP44 proteinKIAA0573 proteinTXNDC4 proteinUNQ532 proteinPRO1075 protein |
Information sourced from Uniprot.org