Human Ep-CAM/CD326 (Epithelial Cell Adhesion Molecule) Antibody Pair (STJAP00392)
General Information
| Short Description | This Ep-CAM/CD326 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | EPCAM |
| Gene ID | 4072 |
| Uniprot ID | EPCAM_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human Ep-CAM/CD326 protien.Detection Immunogen: Recombinant Human Ep-CAM/CD326 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability. |
| Function | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
| Protein Name | Epithelial Cell Adhesion MoleculeEp-CamAdenocarcinoma-Associated AntigenCell Surface Glycoprotein Trop-1Epithelial Cell Surface AntigenEpithelial GlycoproteinEgpEpithelial Glycoprotein 314Egp314Hegp314Ks 1/4 AntigenKsaMajor Gastrointestinal Tumor-Associated Protein Ga733-2Tumor-Associated Calcium Signal Transducer 1Cd Antigen Cd326 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Lateral Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionColocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction |
| Alternative Antibody Pair Names | Epithelial Cell Adhesion Molecule antibody pairEp-Cam antibody pairAdenocarcinoma-Associated Antigen antibody pairCell Surface Glycoprotein Trop-1 antibody pairEpithelial Cell Surface Antigen antibody pairEpithelial Glycoprotein antibody pairEgp antibody pairEpithelial Glycoprotein 314 antibody pairEgp314 antibody pairHegp314 antibody pairKs 1/4 Antigen antibody pairKsa antibody pairMajor Gastrointestinal Tumor-Associated Protein Ga733-2 antibody pairTumor-Associated Calcium Signal Transducer 1 antibody pairCd Antigen Cd326 antibody pairEPCAM antibody pairGA733-2 antibody pairM1S2 antibody pairM4S1 antibody pairMIC18 antibody pairTACSTD1 antibody pairTROP1 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human Ep-CAM/CD326 (Epithelial Cell Adhesion Molecule) Antibody Pair (STJAP00392)
This antibody pair detects human Ep-CAM/CD326 (Epithelial Cell Adhesion Molecule), corresponding to UniProt entry P16422. Reactivity is confirmed for human samples only.
The capture antibody is supplied unconjugated and the detection antibody is biotin-conjugated. Both are goat-derived, antigen affinity-purified antibodies provided at 0.5 mg/mL.
This pair is validated for use in ELISA. It has not been validated for other assay formats based on the available product data.
This antibody pair is suitable for use with serum, plasma, and other biological fluids. All applications are for research use only.
The capture antibody is formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5, while the detection antibody is formulated in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5. Both components should be stored at -20°C for long-term storage, and freeze-thaw cycles should be avoided.
Both the capture and detection antibodies were raised against recombinant human Ep-CAM/CD326 protein. Both antibodies underwent antigen affinity purification.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.