| Host: |
Goat/Goat |
| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
This Ep-CAM/CD326 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Conjugation: |
Unconjugated/Biotin |
| Formulation: |
Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Purification: |
Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Determination Method: |
Colormetric |
| Gene Symbol: |
EPCAM |
| Gene ID: |
4072 |
| Uniprot ID: |
EPCAM_HUMAN |
| Immunogen: |
Capture immunogen: Recombinant Human Ep-CAM/CD326 protien.Detection Immunogen: Recombinant Human Ep-CAM/CD326 protien. |
| Sample Type: |
Serum, plasma and other biological fluids |
| Post Translational Modifications | Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability. |
| Function | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
| Protein Name | Epithelial Cell Adhesion MoleculeEp-CamAdenocarcinoma-Associated AntigenCell Surface Glycoprotein Trop-1Epithelial Cell Surface AntigenEpithelial GlycoproteinEgpEpithelial Glycoprotein 314Egp314Hegp314Ks 1/4 AntigenKsaMajor Gastrointestinal Tumor-Associated Protein Ga733-2Tumor-Associated Calcium Signal Transducer 1Cd Antigen Cd326 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Lateral Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionColocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction |
| Alternative Antibody Pair Names | Epithelial Cell Adhesion Molecule antibody pairEp-Cam antibody pairAdenocarcinoma-Associated Antigen antibody pairCell Surface Glycoprotein Trop-1 antibody pairEpithelial Cell Surface Antigen antibody pairEpithelial Glycoprotein antibody pairEgp antibody pairEpithelial Glycoprotein 314 antibody pairEgp314 antibody pairHegp314 antibody pairKs 1/4 Antigen antibody pairKsa antibody pairMajor Gastrointestinal Tumor-Associated Protein Ga733-2 antibody pairTumor-Associated Calcium Signal Transducer 1 antibody pairCd Antigen Cd326 antibody pairEPCAM antibody pairGA733-2 antibody pairM1S2 antibody pairM4S1 antibody pairMIC18 antibody pairTACSTD1 antibody pairTROP1 antibody pair |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
