SDS-PAGE gel of recombinant human EDF1 protein under reducing conditions stained with Coomassie blue

Human EDF1 protein (Recombinant) (His-Tag) (STJP016795)

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STJP016795
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Short Description :Recombinant-Human EDF1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% Glycerol, 0.1M NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:EDF1
Gene ID:8721
Uniprot ID:EDF1_HUMAN
Accession Number:NP_003783
Immunogen:Human
Immunogen Region:1-148aa
Immunogen Sequence:MAESDWDTVT VLRKKGPTAA QAKSKQAILA AQRRGEDVET SKKWAAGQNK QHSITKNTAK LDRETEELHH DRVTLEVGKV IQQGRQSKGL TQKDLATKIN EKPQVIADYE SGRAIPNNQV LGKIERAIGL KLRGKDIGKP IEKGPRAKLE HHHHHH
Tissue Specificity Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues.
Post Translational Modifications Phosphorylated (by PKA and PKC).
Function Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.
Protein Name Endothelial Differentiation-Related Factor 1
Edf-1
Multiprotein-Bridging Factor 1
Mbf1
Database Links
Cellular Localisation Cytoplasm
Nucleus
Also Nuclear Upon Binding To Nr5a1 And Treatment Of Cells With Tpa Or Forskolin
Alternative Protein Names Endothelial Differentiation-Related Factor 1 protein
Edf-1 protein
Multiprotein-Bridging Factor 1 protein
Mbf1 protein
EDF1 protein

Information sourced from Uniprot.org

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