Human DUSP7 protein (Recombinant) (N-His) (STJP009651)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human DUSP7-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | DUSP7 |
| Gene ID | 1849 |
| Uniprot ID | DUS7_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met100-Leu385 |
Additional Info
| Function | Dual specificity protein phosphatase. Shows high activity towards MAPK1/ERK2. Also has lower activity towards MAPK14 and MAPK8. In arrested oocytes, plays a role in meiotic resumption. Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in oocytes, probably by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB. May also inactivate PRKCA and/or PRKCG. Also important in oocytes for normal chromosome alignment on the metaphase plate and progression to anaphase, where it might regulate activity of the spindle-assembly checkpoint (SAC) complex. |
| Protein Name | Dual Specificity Protein Phosphatase 7Dual Specificity Protein Phosphatase Pyst2 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-202670Reactome: R-HSA-5675221Reactome: R-HSA-9652817 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Dual Specificity Protein Phosphatase 7 proteinDual Specificity Protein Phosphatase Pyst2 proteinDUSP7 proteinPYST2 protein |
Information sourced from Uniprot.org