Human DUSP7 protein (Recombinant) (N-His) (STJP009651)

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STJP009651
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Short Description :Recombinant-Human DUSP7-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:DUSP7
Gene ID:1849
Uniprot ID:DUS7_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met100-Leu385
Function Dual specificity protein phosphatase. Shows high activity towards MAPK1/ERK2. Also has lower activity towards MAPK14 and MAPK8. In arrested oocytes, plays a role in meiotic resumption. Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in oocytes, probably by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB. May also inactivate PRKCA and/or PRKCG. Also important in oocytes for normal chromosome alignment on the metaphase plate and progression to anaphase, where it might regulate activity of the spindle-assembly checkpoint (SAC) complex.
Protein Name Dual Specificity Protein Phosphatase 7
Dual Specificity Protein Phosphatase Pyst2
Database Links Reactome: R-HSA-112409
Reactome: R-HSA-202670
Reactome: R-HSA-5675221
Reactome: R-HSA-9652817
Cellular Localisation Cytoplasm
Alternative Protein Names Dual Specificity Protein Phosphatase 7 protein
Dual Specificity Protein Phosphatase Pyst2 protein
DUSP7 protein
PYST2 protein

Information sourced from Uniprot.org

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