Human DOC2B protein (Recombinant) (N-His) (STJP005386)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human DOC2B-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | DOC2B |
| Gene ID | 8447 |
| Uniprot ID | DOC2B_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly173-Arg397 |
Additional Info
| Function | Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes. |
| Protein Name | Double C2-Like Domain-Containing Protein BetaDoc2-Beta |
| Database Links | |
| Cellular Localisation | CytoplasmCytoplasmic GranuleCell MembranePeripheral Membrane ProteinTranslocates To The Plasma Membrane In A Calcium-Dependent Manner |
| Alternative Protein Names | Double C2-Like Domain-Containing Protein Beta proteinDoc2-Beta proteinDOC2B proteinDOC2BL protein |
Information sourced from Uniprot.org