Human DIMT1 protein (Recombinant) (His-Tag) (STJP017731)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DIMT1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 30% Glycerol, 2mM DTT, 200mM NaCl, 2mM EDTA |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DIMT1 |
| Gene ID | 27292 |
| Uniprot ID | DIM1_HUMAN |
| Accession Number | NP_055288 |
| Immunogen | Human |
| Immunogen Region | 1-313aa |
| Immunogen Sequence |
Additional Info
| Function | Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Dimethyladenosine Transferase18s RrnaAdenine(1779-N(6/Adenine(1780-N(6-Dimethyltransferase18s Rrna DimethylaseDim1 Dimethyladenosine Transferase 1 HomologDim1 Dimethyladenosine Transferase 1-LikeS-Adenosylmethionine-6-N' -N'-Adenosyl(Rrna Dimethyltransferase |
| Database Links | Reactome: R-HSA-6790901 |
| Cellular Localisation | NucleusNucleoplasmNucleolus |
| Alternative Protein Names | Dimethyladenosine Transferase protein18s Rrna proteinAdenine(1779-N(6/Adenine(1780-N(6-Dimethyltransferase protein18s Rrna Dimethylase proteinDim1 Dimethyladenosine Transferase 1 Homolog proteinDim1 Dimethyladenosine Transferase 1-Like proteinS-Adenosylmethionine-6-N' -N'-Adenosyl(Rrna Dimethyltransferase proteinDIMT1 proteinDIMT1L proteinHUSSY-05 protein |
Information sourced from Uniprot.org