Human DIMT1 protein (Recombinant) (His-Tag) (STJP017731)

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STJP017731
£112.50 - £597.50
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Short Description :Recombinant-Human DIMT1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 30% Glycerol, 2mM DTT, 200mM NaCl, 2mM EDTA
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:DIMT1
Gene ID:27292
Uniprot ID:DIM1_HUMAN
Accession Number:NP_055288
Immunogen:Human
Immunogen Region:1-313aa
Immunogen Sequence:MPKVKSGAI GRRRGRQEQR RELKSAGGLM FNTGIGQHIL KNPLIINSII DKAALRPTDV VLEVGPGTGN MTVKLLEKAK KVVACELDPR LVAELHKRVQ GTPVASKLQV LVGDVLKTDL PFFDTCVANL PYQISSPFVF KLLLHRPFFR CAILMFQREF ALRLVAKPGD KLYCRLSINT QLLARVDHLM KVGKNNFRPP PKVESS
Function Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Protein Name Dimethyladenosine Transferase
18s Rrna
Adenine(1779-N(6/Adenine(1780-N(6-Dimethyltransferase
18s Rrna Dimethylase
Dim1 Dimethyladenosine Transferase 1 Homolog
Dim1 Dimethyladenosine Transferase 1-Like
S-Adenosylmethionine-6-N' -N'-Adenosyl(Rrna Dimethyltransferase
Database Links Reactome: R-HSA-6790901
Cellular Localisation Nucleus
Nucleoplasm
Nucleolus
Alternative Protein Names Dimethyladenosine Transferase protein
18s Rrna protein
Adenine(1779-N(6/Adenine(1780-N(6-Dimethyltransferase protein
18s Rrna Dimethylase protein
Dim1 Dimethyladenosine Transferase 1 Homolog protein
Dim1 Dimethyladenosine Transferase 1-Like protein
S-Adenosylmethionine-6-N' -N'-Adenosyl(Rrna Dimethyltransferase protein
DIMT1 protein
DIMT1L protein
HUSSY-05 protein

Information sourced from Uniprot.org