Human DFF45/ICAD protein (Recombinant) (His-Tag) (STJP016510)

SKU:
STJP016510
£134.50 - £738.50
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Short Description :Recombinant-Human DFF45/ICAD-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:DFFA
Gene ID:1676
Uniprot ID:DFFA_HUMAN
Accession Number:AAH07721.1
Immunogen:Human
Immunogen Region:1-331aa
Immunogen Sequence: MEVTGDAGVP ESGEIRTLKP CLLRRNYSRE QHGVAASCLE DLRSKACDIL AIDKSLTPVT LVLAEDGTIV DDDDYFLCLP SNTKFVALAS NEKWAYNNSD GGTAWISQES FDVDETDSGA GLKWKNVARQ LKEDLSSIIL LSEEDLQMLV DAPCSDLAQE LRQSCATVQR LQHTLQQVLD QREEVRQSKQ LLQLYLQALE KEGSLL
Post Translational Modifications Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
Function Inhibitor of the caspase-activated DNase (DFF40).
Protein Name Dna Fragmentation Factor Subunit Alpha
Dna Fragmentation Factor 45 Kda Subunit
Dff-45
Inhibitor Of Cad
Icad
Database Links Reactome: R-HSA-140342
Cellular Localisation Cytoplasm
Alternative Protein Names Dna Fragmentation Factor Subunit Alpha protein
Dna Fragmentation Factor 45 Kda Subunit protein
Dff-45 protein
Inhibitor Of Cad protein
Icad protein
DFFA protein
DFF1 protein
DFF45 protein
H13 protein

Information sourced from Uniprot.org