Human DFF45/ICAD protein (Recombinant) (His-Tag) (STJP016510)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DFF45/ICAD-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DFFA |
| Gene ID | 1676 |
| Uniprot ID | DFFA_HUMAN |
| Accession Number | AAH07721.1 |
| Immunogen | Human |
| Immunogen Region | 1-331aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. |
| Function | Inhibitor of the caspase-activated DNase (DFF40). |
| Protein Name | Dna Fragmentation Factor Subunit AlphaDna Fragmentation Factor 45 Kda SubunitDff-45Inhibitor Of CadIcad |
| Database Links | Reactome: R-HSA-140342 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Dna Fragmentation Factor Subunit Alpha proteinDna Fragmentation Factor 45 Kda Subunit proteinDff-45 proteinInhibitor Of Cad proteinIcad proteinDFFA proteinDFF1 proteinDFF45 proteinH13 protein |
Information sourced from Uniprot.org