Human DESI1 protein (Recombinant) (His-Tag) (STJP018347)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DESI1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DESI1 |
| Gene ID | 27351 |
| Uniprot ID | DESI1_HUMAN |
| Accession Number | NP_056519 |
| Immunogen | Human |
| Immunogen Region | 1-168aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMEPPNLY PVKLYVYDLS KGLARRLSPI MLGKQLEGIW HTSIVVHKDE FFFGSGGISS CPPGGTLLGP PDSVVDVGST EVTEEIFLEY LSSLGESLFR GEAYNLFEHN CNTFSNEVAQ FLTGRKIPSY ITDLPSEVLS TPFGQALRPL LDSIQIQPPG GSSVGRPNGQ S |
Additional Info
| Function | Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46. Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm. Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5). |
| Protein Name | Desumoylating Isopeptidase 1Desi-1Pppde Peptidase Domain-Containing Protein 2Palmitoyl Protein Thioesterase Desi1Polyubiquitinated Substrate TransporterPostS-Depalmitoylase Desi1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Nucleus And The CytoplasmExported From The Nucleus In A Xpo1/Crm1-Dependent Manner Via Its Nuclear Export Signal Motifs |
| Alternative Protein Names | Desumoylating Isopeptidase 1 proteinDesi-1 proteinPppde Peptidase Domain-Containing Protein 2 proteinPalmitoyl Protein Thioesterase Desi1 proteinPolyubiquitinated Substrate Transporter proteinPost proteinS-Depalmitoylase Desi1 proteinDESI1 proteinFAM152B proteinPPPDE2 protein |
Information sourced from Uniprot.org