Human Cysteine Conjugate beta-Lyase/CCBL1 protein (Recombinant) (His-Tag) (STJP019176)

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STJP019176
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Cysteine Conjugate beta-Lyase/CCBL1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: KYAT1
Gene ID: 883
Uniprot ID: KAT1_HUMAN
Immunogen Region: 1-422aa
Accession Number: NP_004050
Immunogen: Human
Immunogen Sequence: MAKQLQA RRLDGIDYNP WVEFVKLASE HDVVNLGQGF PDFPPPDFAV EAFQHAVSGD FMLNQYTKTF GYPPLTKILA SFFGELLGQE IDPLRNVLVT VGGYGALFTA FQALVDEGDE VIIIEPFFDC YEPMTMMAGG RPVFVSLKPG PIQNGELGSS SNWQLDPMEL AGKFTSRTKA LVLNTPNNPL GKVFSREELE LVASLC
Function Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.
Protein Name Kynurenine--Oxoglutarate Transaminase 1
Cysteine-S-Conjugate Beta-Lyase
Glutamine Transaminase K
Gtk
Glutamine--Phenylpyruvate Transaminase
Kynurenine Aminotransferase 1
Kynurenine Aminotransferase I
Kati
Kynurenine--Oxoglutarate Transaminase I
Database Links Reactome: R-HSA-71240
Reactome: R-HSA-8964208
Reactome: R-HSA-8964539
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Kynurenine--Oxoglutarate Transaminase 1 protein
Cysteine-S-Conjugate Beta-Lyase protein
Glutamine Transaminase K protein
Gtk protein
Glutamine--Phenylpyruvate Transaminase protein
Kynurenine Aminotransferase 1 protein
Kynurenine Aminotransferase I protein
Kati protein
Kynurenine--Oxoglutarate Transaminase I protein
KYAT1 protein
CCBL1 protein

Information sourced from Uniprot.org

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