Human Cysteine Conjugate beta-Lyase/CCBL1 protein (Recombinant) (His-Tag) (STJP019176)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Cysteine Conjugate beta-Lyase/CCBL1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KYAT1 |
| Gene ID | 883 |
| Uniprot ID | KAT1_HUMAN |
| Accession Number | NP_004050 |
| Immunogen | Human |
| Immunogen Region | 1-422aa |
| Immunogen Sequence |
Additional Info
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. |
| Protein Name | Kynurenine--Oxoglutarate Transaminase 1Cysteine-S-Conjugate Beta-LyaseGlutamine Transaminase KGtkGlutamine--Phenylpyruvate TransaminaseKynurenine Aminotransferase 1Kynurenine Aminotransferase IKatiKynurenine--Oxoglutarate Transaminase I |
| Database Links | Reactome: R-HSA-71240Reactome: R-HSA-8964208Reactome: R-HSA-8964539 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Kynurenine--Oxoglutarate Transaminase 1 proteinCysteine-S-Conjugate Beta-Lyase proteinGlutamine Transaminase K proteinGtk proteinGlutamine--Phenylpyruvate Transaminase proteinKynurenine Aminotransferase 1 proteinKynurenine Aminotransferase I proteinKati proteinKynurenine--Oxoglutarate Transaminase I proteinKYAT1 proteinCCBL1 protein |
Information sourced from Uniprot.org