| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Cystatin-M/CST6-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate Z-FR-AMC. The IC50 value is approximately 16 nM. |
| Gene Symbol: |
CST6 |
| Gene ID: |
1474 |
| Uniprot ID: |
CYTM_HUMAN |
| Immunogen Region: |
Arg29-Met149 |
| Immunogen: |
Recombinant Human Cystatin-M/CST6 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Arg29-Met149) of human CST6 (Accession #NP_001314.1) fused with a 6×His tag at the C-terminus. |
| Post Translational Modifications | Substrate for transglutaminases. Acts as an acyl acceptor but not as an acyl donor. |
| Function | High affinity inhibitor for cathepsin L, cathepsin L2 (cathepsin V), and legumain. Involved in the regulation of epidermal cornification, and hair follicle morphogenesis and maintenance. |
| Protein Name | Cystatin-MCystatin-6Cystatin-E |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cystatin-M proteinCystatin-6 proteinCystatin-E proteinCST6 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
