Human Cystatin-SA/CST2 protein (Recombinant) (C-His) (STJP002724)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Cystatin-SA/CST2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp21-Ala141) of human Cystatin SA/CST2 (Accession #NP_001313.1) fused with a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Cystatin-SA/CST2-C-His protein was developed in hek293 cells using the region Trp21-Ala141. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of 50mM Tris, 150mM NaCl, pH 8.0. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC. The IC50 value is<2.5 nM. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CST2 |
| Gene ID | 1470 |
| Uniprot ID | CYTT_HUMAN |
| Immunogen | Recombinant Human Cystatin-SA/CST2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp21-Ala141) of human Cystatin SA/CST2 (Accession #NP_001313.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Region | Trp21-Ala141 |
| Immunogen Sequence | WSPQEEDRIIEGGIYDADLN DERVQRALHFVISEYNKATE DEYYRRLLRVLRAREQIVGG VNYFFDIEVGRTICTKSQPN LDTCAFHEQPELQKKQLCSF QIYEVPWEDRMSLVNSRCQE A |
Additional Info
| Function | Thiol protease inhibitor. |
| Protein Name | Cystatin-SaCystatin-2Cystatin-S5 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cystatin-Sa proteinCystatin-2 proteinCystatin-S5 proteinCST2 protein |
Information sourced from Uniprot.org