| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Cystatin-SN/CST1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC. The IC50 value is |
| Gene Symbol: |
CST1 |
| Gene ID: |
1469 |
| Uniprot ID: |
CYTN_HUMAN |
| Immunogen Region: |
Trp21-Ser141 |
| Immunogen: |
Recombinant Human Cystatin-SN/CST1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp21-Ser141) of human Cystatin SN/CST1 (Accession #NP_001889.2) fused with a 6×His tag at the C-terminus. |
| Function | Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. |
| Protein Name | Cystatin-SnCystain-Sa-ICystatin-1Salivary Cystatin-Sa-1 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cystatin-Sn proteinCystain-Sa-I proteinCystatin-1 proteinSalivary Cystatin-Sa-1 proteinCST1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
