Human Cyclophilin B/PPIB protein (Recombinant) (No-Tag) (STJP019603)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Cyclophilin B/PPIB-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20mM NaCl, 0.5mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity | Specific activity is > 1, 500nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin. |
Target Information
| Gene Symbol | PPIB |
| Gene ID | 5479 |
| Uniprot ID | PPIB_HUMAN |
| Accession Number | NP_000933 |
| Immunogen | Human |
| Immunogen Region | 26-216aa |
| Immunogen Sequence | MLLPGPSAAD EKKKGPKVTV KVYFDLRIGD EDVGRVIFGL FGKTVPKTVD NFVALATGEK GFGYKNSKFH RVIKDFMIQG GDFTRGDGTG GKSIYGERFP DENFKLKHYG PGWVSMANAG KDTNGSQFFI TTVKTAWLDG KHVVFGKVLE GMEVVRKVES TKTDSRDKPL KDVIIADCGK IEVEKPFAIA KE |
Additional Info
| Function | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase BPpiase BCyp-S1Cyclophilin BRotamase BS-CyclophilinScylp |
| Database Links | Reactome: R-HSA-1650814Reactome: R-HSA-9692916 |
| Cellular Localisation | Virion(Microbial Infection)Endoplasmic Reticulum LumenMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Protein Names | Peptidyl-Prolyl Cis-Trans Isomerase B proteinPpiase B proteinCyp-S1 proteinCyclophilin B proteinRotamase B proteinS-Cyclophilin proteinScylp proteinPPIB proteinCYPB protein |
Information sourced from Uniprot.org