Human Crystallin zeta/CRYZ protein (Recombinant) (His-Tag) (STJP018846)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Crystallin zeta/CRYZ-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRYZ |
| Gene ID | 1429 |
| Uniprot ID | QOR_HUMAN |
| Accession Number | NP_001123514 |
| Immunogen | Human |
| Immunogen Region | 1-329aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Only very low amounts in the lens. |
| Function | Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding. |
| Protein Name | Quinone OxidoreductaseNadph -Quinone ReductaseZeta-Crystallin |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Quinone Oxidoreductase proteinNadph -Quinone Reductase proteinZeta-Crystallin proteinCRYZ protein |
Information sourced from Uniprot.org