Human Crystallin mu/CRYM protein (Recombinant) (His-Tag) (STJP016699)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Crystallin mu/CRYM-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRYM |
| Gene ID | 1428 |
| Uniprot ID | CRYM_HUMAN |
| Accession Number | NP_001879 |
| Immunogen | Human |
| Immunogen Region | 1-314aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH> MSRVPAFLSA AEVEEHLRSS SLLIPPLETA LANFSSGPEG |
Additional Info
| Tissue Specificity | Expressed in neural tissues, muscle and kidney. Expressed in the inner ear. |
| Function | Catalyzes the NAD(P)H-dependent reduction of imine double bonds of a number of cyclic ketimine substrates, including sulfur-containing cyclic ketimines. Under physiological conditions, it efficiently catalyzes delta(1)-piperideine-2-carboxylate (P2C) and delta(1)-pyrroline-2-carboxylate (Pyr2C) reduction, suggesting a central role in lysine and glutamate metabolism. Additional substrates are delta(2)-thiazoline-2-carboxylate (T2C), 3,4-dehydrothiomorpholine-3-carboxylate (AECK), and (R)-lanthionine ketimine (LK) that is reduced at very low rate compared to other substrates. Also catalyzes the NAD(P)H-dependent reduction of (S)-cystathionine ketimine (CysK). |
| Protein Name | Ketimine Reductase Mu-Crystallin1-Piperideine-2-Carboxylate/1-Pyrroline-2-Carboxylate ReductaseP2c/Pyr2c ReductaseNadp-Regulated Thyroid-Hormone-Binding Protein |
| Database Links | Reactome: R-HSA-71064 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Ketimine Reductase Mu-Crystallin protein1-Piperideine-2-Carboxylate/1-Pyrroline-2-Carboxylate Reductase proteinP2c/Pyr2c Reductase proteinNadp-Regulated Thyroid-Hormone-Binding Protein proteinCRYM proteinTHBP protein |
Information sourced from Uniprot.org