SDS-PAGE gel of recombinant human COQ9 protein 3 µg under reducing conditions with Coomassie blue staining

Human COQ9 protein (Recombinant) (His-Tag) (STJP019127)

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STJP019127
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Short Description :Recombinant-Human COQ9-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:COQ9
Gene ID:57017
Uniprot ID:COQ9_HUMAN
Accession Number:NP_064708
Immunogen:Human
Immunogen Region:45-318aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSRSSDEQK QQPPNSFSQQ HSETQGAEKP DPESSHSPPR YTDQGGEEEE DYESEEQLQH RILTAALEFV PAHGWTAEAI AEGAQSLGLS SAAASMFGKD GSELILHFVT QCNTRLTRVL EEEQKLVQLG QAEKRKTDQF LRDAVETRLR MLIPYIEHWP RALSILMLPH NIPSSLSLLT SMVDDMWHYA GDQSTDFNWY TRRAMLAA
Post Translational Modifications In response to mitochondrial stress, the precursor protein is ubiquitinated by the SIFI complex in the cytoplasm before mitochondrial import, leading to its degradation. Within the SIFI complex, UBR4 initiates ubiquitin chain that are further elongated or branched by KCMF1.
Function Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to COQ7, therefore facilitating the COQ7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Protein Name Ubiquinone Biosynthesis Protein Coq9 - Mitochondrial
Database Links Reactome: R-HSA-2142789
Cellular Localisation Mitochondrion
Associates With Cardiolipin-Rich Membranes Which Leads To The Lipid Bilayer Deformation And Then Accessing To Membrane-Bound Lipids
Alternative Protein Names Ubiquinone Biosynthesis Protein Coq9 - Mitochondrial protein
COQ9 protein
C16orf49 protein
HSPC326 protein
PSEC0129 protein

Information sourced from Uniprot.org

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