Human COLEC11 protein (Recombinant) (N-His) (STJP009708)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human COLEC11-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | COLEC11 |
| Gene ID | 78989 |
| Uniprot ID | COL11_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser151-Met271 |
Additional Info
| Function | Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis. |
| Protein Name | Collectin-11Collectin Kidney Protein 1Cl-K1 |
| Database Links | Reactome: R-HSA-166662Reactome: R-HSA-166663Reactome: R-HSA-3000480 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Collectin-11 proteinCollectin Kidney Protein 1 proteinCl-K1 proteinCOLEC11 proteinUNQ596 proteinPRO1182 protein |
Information sourced from Uniprot.org