Human COLEC11 protein (Recombinant) (N-His) (STJP009708)

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STJP009708
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Short Description :Recombinant-Human COLEC11-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:COLEC11
Gene ID:78989
Uniprot ID:COL11_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ser151-Met271
Function Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis.
Protein Name Collectin-11
Collectin Kidney Protein 1
Cl-K1
Database Links Reactome: R-HSA-166662
Reactome: R-HSA-166663
Reactome: R-HSA-3000480
Cellular Localisation Secreted
Alternative Protein Names Collectin-11 protein
Collectin Kidney Protein 1 protein
Cl-K1 protein
COLEC11 protein
UNQ596 protein
PRO1182 protein

Information sourced from Uniprot.org