Human CNBP protein (Recombinant) (N-His-SUMO) (STJP008933)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CNBP-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CNBP |
| Gene ID | 7555 |
| Uniprot ID | CNBP_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Tyr99-Thr172 |
Additional Info
| Post Translational Modifications | Arginine methylation by PRMT1 in the Arg/Gly-rich region impedes RNA binding. |
| Function | Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression. Has a role as transactivator of the Myc promoter. Binds single-stranded RNA in a sequence-specific manner. Isoform 1: Binds G-rich elements in target mRNA coding sequences. Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs. Isoform 2: Binds to RNA. Isoform 4: Binds to RNA. Isoform 5: Binds to RNA. Isoform 6: Binds to RNA. Isoform 8: Binds to RNA. |
| Protein Name | Cchc-Type Zinc Finger Nucleic Acid Binding ProteinCellular Nucleic Acid-Binding ProteinCnbpZinc Finger Protein 9 |
| Database Links | Reactome: R-HSA-9705671 |
| Cellular Localisation | NucleusCytoplasmEndoplasmic ReticulumIsoform 1: CytoplasmIsoform 2: CytoplasmIsoform 4: CytoplasmIsoform 5: CytoplasmIsoform 6: CytoplasmIsoform 8: Cytoplasm |
| Alternative Protein Names | Cchc-Type Zinc Finger Nucleic Acid Binding Protein proteinCellular Nucleic Acid-Binding Protein proteinCnbp proteinZinc Finger Protein 9 proteinCNBP proteinRNF163 proteinZNF9 protein |
Information sourced from Uniprot.org