Human CNBP protein (Recombinant) (N-His-SUMO) (STJP008933)

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STJP008933
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CNBP-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CNBP
Gene ID: 7555
Uniprot ID: CNBP_HUMAN
Immunogen Region: Tyr99-Thr172
Immunogen: Homo sapiens (Human)
Post Translational Modifications Arginine methylation by PRMT1 in the Arg/Gly-rich region impedes RNA binding.
Function Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression. Has a role as transactivator of the Myc promoter. Binds single-stranded RNA in a sequence-specific manner. Isoform 1: Binds G-rich elements in target mRNA coding sequences. Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs. Isoform 2: Binds to RNA. Isoform 4: Binds to RNA. Isoform 5: Binds to RNA. Isoform 6: Binds to RNA. Isoform 8: Binds to RNA.
Protein Name Cchc-Type Zinc Finger Nucleic Acid Binding Protein
Cellular Nucleic Acid-Binding Protein
Cnbp
Zinc Finger Protein 9
Database Links Reactome: R-HSA-9705671
Cellular Localisation Nucleus
Cytoplasm
Endoplasmic Reticulum
Isoform 1: Cytoplasm
Isoform 2: Cytoplasm
Isoform 4: Cytoplasm
Isoform 5: Cytoplasm
Isoform 6: Cytoplasm
Isoform 8: Cytoplasm
Alternative Protein Names Cchc-Type Zinc Finger Nucleic Acid Binding Protein protein
Cellular Nucleic Acid-Binding Protein protein
Cnbp protein
Zinc Finger Protein 9 protein
CNBP protein
RNF163 protein
ZNF9 protein

Information sourced from Uniprot.org

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