SDS-PAGE gel of recombinant human CLIC2 protein stained with Coomassie blue

Human CLIC2 protein (Recombinant) (His-Tag) (STJP017156)

SKU:
STJP017156
£134.50 - £738.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Recombinant-Human CLIC2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl and 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:CLIC2
Gene ID:1193
Uniprot ID:CLIC2_HUMAN
Accession Number:NP_001280
Immunogen:Human
Immunogen Region:1-247aa
Immunogen Sequence: MSGLRPGTQV DPEIELFVKA GSDGESIGNC PFCQRLFMIL WLKGVKFNVT TVDMTRKPEE LKDLAPGTNP PFLVYNKELK TDFIKIEEFL EQTLAPPRYP HLSPKYKESF DVGCNLFAKF SAYIKNTQKE ANKNFEKSLL KEFKRLDDYL NTPLLDEIDP DSAEEPPVSR RLFLDGDQLT LADCSLLPKL NIIKVAAKKY RDFDI
Tissue Specificity Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis. Expressed in fetal thymus and kidney.
Function In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Displays weak glutathione peroxidase activity (Probable). Can insert into membranes and form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
Protein Name Chloride Intracellular Channel Protein 2
Glutaredoxin-Like Oxidoreductase Clic2
Glutaredoxin-Like Peroxidase Clic2
Xap121
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-5578775
Cellular Localisation Cytoplasm
Membrane
Single-Pass Membrane Protein
Exists Both As Soluble Cytoplasmic Protein And As Membrane Protein With Probably A Single Transmembrane Domain
Alternative Protein Names Chloride Intracellular Channel Protein 2 protein
Glutaredoxin-Like Oxidoreductase Clic2 protein
Glutaredoxin-Like Peroxidase Clic2 protein
Xap121 protein
CLIC2 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP014260 Human CLIC2 protein (Recombinant) (N-His) (STJP014260) E.coli ELISA/WB
STJP019170 Human FGB protein (Recombinant) (His-Tag) (STJP019170) E.coli SDS-PAGE
STJP019149 Human PYCR2 protein (Recombinant) (His-Tag) (STJP019149) E.coli SDS-PAGE
STJP019163 Human ALDH6A1 protein (Recombinant) (His-Tag) (STJP019163) E.coli SDS-PAGE
STJP019189 Human UBE2Q2 protein (Recombinant) (His-Tag) (STJP019189) E.coli SDS-PAGE

Related Products

!