| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human CLEC12A/MICL/CLL-1-N-hFc-Avi protein was developed from hek293 and has a target region of N-hFc-Avi. For use in research applications. |
| Conjugation: |
Biotin |
| Formulation: |
Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
| Dilution Range: |
Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
| Storage Instruction: |
The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
| Gene Symbol: |
CLEC12A |
| Gene ID: |
160364 |
| Uniprot ID: |
CL12A_HUMAN |
| Immunogen Region: |
His65-Ala265 |
| Immunogen: |
DNA sequence encoding Human CLEC12A/MICL/CLL-1 including a N-hFc-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
| Post Translational Modifications | Highly N-glycosylated. Glycosylation varies between cell types. |
| Function | Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. |
| Protein Name | C-Type Lectin Domain Family 12 Member AC-Type Lectin-Like Molecule 1Cll-1Dendritic Cell-Associated Lectin 2Dcal-2Myeloid Inhibitory C-Type Lectin-Like ReceptorMiclCd Antigen Cd371 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinLigand Binding Leads To Internalization |
| Alternative Protein Names | C-Type Lectin Domain Family 12 Member A proteinC-Type Lectin-Like Molecule 1 proteinCll-1 proteinDendritic Cell-Associated Lectin 2 proteinDcal-2 proteinMyeloid Inhibitory C-Type Lectin-Like Receptor proteinMicl proteinCd Antigen Cd371 proteinCLEC12A proteinCLL1 proteinDCAL2 proteinMICL protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
