Human CES3 protein (Recombinant) (N-His) (STJP005600)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CES3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CES3 |
| Gene ID | 23491 |
| Uniprot ID | EST3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser398-Gln568 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-4-(1-piperidino)-1-piperidino-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics. |
| Protein Name | Carboxylesterase 3Liver Carboxylesterase 31 Homolog |
| Database Links | Reactome: R-HSA-211945Reactome: R-HSA-8964038 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Protein Names | Carboxylesterase 3 proteinLiver Carboxylesterase 31 Homolog proteinCES3 proteinUNQ869 proteinPRO1887 protein |
Information sourced from Uniprot.org