Human CENPB protein (Recombinant) (N-His) (STJP010831)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CENPB-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CENPB |
| Gene ID | 1059 |
| Uniprot ID | CENPB_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser181-Gly392 |
Additional Info
| Function | Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes (Probable). |
| Protein Name | Major Centromere Autoantigen BCentromere Protein BCenp-B |
| Database Links | |
| Cellular Localisation | NucleusChromosomeCentromere |
| Alternative Protein Names | Major Centromere Autoantigen B proteinCentromere Protein B proteinCenp-B proteinCENPB protein |
Information sourced from Uniprot.org