| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CENPB-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | CENPB |
| Gene ID: | 1059 |
| Uniprot ID: | CENPB_HUMAN |
| Immunogen Region: | Ser181-Gly392 |
| Immunogen: | Homo sapiens (Human) |
| Function | Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes (Probable). |
| Protein Name | Major Centromere Autoantigen BCentromere Protein BCenp-B |
| Cellular Localisation | NucleusChromosomeCentromere |
| Alternative Protein Names | Major Centromere Autoantigen B proteinCentromere Protein B proteinCenp-B proteinCENPB protein |
Information sourced from Uniprot.org