Human CDK16 (Cyclin Dependent Kinase 16) Sandwich ELISA Kit (STJE0007848)
SPECIFICATIONS
General Information
| Short Description | This CDK16 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 12.6pg/mL |
| Detection Limit | 31.2-2000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | CDK16 |
| Gene ID | 5127 |
| Uniprot ID | CDK16_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in pancreas islets (at protein level). Detected in brain and pancreas. |
| Post Translational Modifications | Phosphorylation of CDK16 is essential for the binding of CCNY, but also essential for the regulation of CDK16 kinase activity. Phosphorylation of CDK16 is essential for the binding of CCNYl1, but also essential for the regulation of CDK16 kinase activity. Ser-146 and Ser-153 are the most critical sites for the binding of CCNYL1 and for modulating CDK16 kinase activity. Phosphorylation at Ser-153 inhibits kinase activity. |
| Function | Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development. Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro). |
| Protein Name | Cyclin-Dependent Kinase 16Cell Division Protein Kinase 16Pctaire-Motif Protein Kinase 1Serine/Threonine-Protein Kinase Pctaire-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoplasmic VesicleSecretory VesicleCell MembranePeripheral Membrane ProteinCytoplasmic SideSynapseSynaptosomeColocalizes With Insulin In Pancreas IsletsRecruited To The Cell Membrane By Ccny |
| Alternative ELISA Names | Cyclin-Dependent Kinase 16 ELISA kitCell Division Protein Kinase 16 ELISA kitPctaire-Motif Protein Kinase 1 ELISA kitSerine/Threonine-Protein Kinase Pctaire-1 ELISA kitCDK16 ELISA kitPCTAIRE1 ELISA kitPCTK1 ELISA kit |
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Information sourced from Uniprot.org