Human CD77/A4GALT protein (Recombinant) (N-His) (STJP006702)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD77/A4GALT-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | A4GALT |
| Gene ID | 53947 |
| Uniprot ID | A4GAT_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly44-Leu353 |
Additional Info
| Function | Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer. Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (Probable). Globotriaosylceramide/globoside Gb3Cer in blood and tissue cell membranes is the antigen Pk of blood histogroup P. (Microbial infection) Globotriaosylceramide is one of the cellular ligands for bacterial verotoxins. |
| Protein Name | Lactosylceramide 4-Alpha-GalactosyltransferaseAlpha-1 -4-N-AcetylglucosaminyltransferaseAlpha-1 -4-GalactosyltransferaseAlpha4gal-T1Cd77 SynthaseGlobotriaosylceramide SynthaseGb3 SynthaseP1/Pk SynthaseUdp-Galactose -Beta-D-Galactosyl-Beta1-R 4-Alpha-D-Galactosyltransferase |
| Database Links | Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Lactosylceramide 4-Alpha-Galactosyltransferase proteinAlpha-1 -4-N-Acetylglucosaminyltransferase proteinAlpha-1 -4-Galactosyltransferase proteinAlpha4gal-T1 proteinCd77 Synthase proteinGlobotriaosylceramide Synthase proteinGb3 Synthase proteinP1/Pk Synthase proteinUdp-Galactose -Beta-D-Galactosyl-Beta1-R 4-Alpha-D-Galactosyltransferase proteinA4GALT proteinA14GALT proteinA4GALT1 protein |
Information sourced from Uniprot.org