Human CD66b (CEACAM8) protein (Recombinant) (STJP000513)

Name: Human CD66b (CEACAM8) protein (Recombinant) (STJP000513)
SKU: STJP000513
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostHEK293

ConjugationUnconjugated

ImmunogenOptimized DNA sequence encoding extracellular domain of human CD66bincluding a C-terminal 6His tag was expressed in HEK293 cells. NA

STJP000513

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Short Description	Recombinant-Human CD66b (CEACAM8)-protein was developed from hek293. For use in research applications.
Host	HEK293
Note	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Formulation	0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity	The activity was tested by immobilized recombinant CD66a (10ug/ml) ability to bind recombinant human CD66b in functional ELISA. NA

Gene Symbol	CEACAM8
Gene ID	1088
Uniprot ID	CEAM8_HUMAN
Immunogen	Optimized DNA sequence encoding extracellular domain of human CD66bincluding a C-terminal 6His tag was expressed in HEK293 cells. NA
Immunogen Region	ECD

Tissue Specificity	Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
Post Translational Modifications	Glycosylated.
Function	Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
Protein Name	Cell Adhesion Molecule Ceacam8 Cd67 Antigen Carcinoembryonic Antigen Cgm6 Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 Cea Cell Adhesion Molecule 8 Non-Specific Cross-Reacting Antigen Nca-95 Cd Antigen Cd66b
Database Links	Reactome: R-HSA-1566977 Reactome: R-HSA-202733 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Cell Surface
Alternative Protein Names	Cell Adhesion Molecule Ceacam8 protein Cd67 Antigen protein Carcinoembryonic Antigen Cgm6 protein Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 protein Cea Cell Adhesion Molecule 8 protein Non-Specific Cross-Reacting Antigen Nca-95 protein Cd Antigen Cd66b protein CEACAM8 protein CGM6 protein

Information sourced from Uniprot.org